In turn, more of it enters the bloodstream and remains in the body longer. This doesn’t allow the body to metabolize the drug. Grapefruit juice can inhibit the activity of that enzyme. You see, the CYP3A4 enzyme in the small intestine is necessary for the metabolism of many drugs in the body. This can have a major impact on blood vessels, which could lead to heart failure. The same problems could occur by combining this citrus fruit with blood pressure medication. When the blood levels of these active compounds are high, a person is more likely to experience side effects.įor instance, eating too much grapefruit or drinking too much grapefruit juice while taking cholesterol-lowering medications such as statins leads to a high concentration of the drug in the body.Īs a result, the risk of muscle and liver damage increases. In most cases, grapefruit juice lets more of the main active ingredient of the drug enter the blood. How grapefruit can affect some medicationsĪlthough grapefruit and grapefruit juice can be refreshing, it’s best to avoid them when taking certain medications. Since the manufacturer lost the patent for the drug molecule, many low-cost generics and free pills are available on the market. Food and Drug Administration (FDA) approved this prescription medication in 1997. Flomax is one of the most frequently prescribed medications among older men for this medical condition. The medication works by relaxing the muscles in the bladder neck and prostate gland, thus making it easier for patients to urinate. What is Flomax?įlomax (tamsulosin) is an alpha-blocker prescription drug for men with benign prostatic hyperplasia. Is this true?ĭo you need to avoid grapefruit if you’re taking Flomax? Scroll down to learn more about Flomax and grapefruit. You’ve probably come across claims this medication interacts with grapefruit. Tamsulosin (Flomax) is a medication commonly prescribed for enlarged prostate. The prevalence of this prostate condition increases with age.įor example, BPH affects about 50% of men older than 50 years and is histologically evident in 90% of men by the time they turn 85 years of age. Alternatives to grapefruit and grapefruit juiceīenign prostatic hyperplasia (BPH), or enlarged prostate, affects millions of men around the globe.Other prostate medications grapefruit can interfere with. Other things to avoid while taking Flomax.Is it safe to have grapefruit while taking Flomax?.How grapefruit can affect some medications.
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